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April 21, 2008

Study: Cholesterol raises Alzheimer's risk

By Monifa Thomas

Avoiding heart disease isn't the only reason to keep your cholesterol in check. A new study has found the risk of developing Alzheimer's disease is higher for people who, in their 40s, have high cholesterol.

Alzheimer's is also more likely to start early for heavy drinkers and smokers, according to a separate study presented Wednesday at the American Academy of Neurology conference in Chicago.

A study of nearly 9,800 men and women from northern California found that people who had high cholesterol levels in their early 40s were at least 1.25 times more likely to develop Alzheimer's disease by the time they reached their 70s.

"High mid-life cholesterol increased the risk of Alzheimer's disease regardless of mid-life diabetes, high blood pressure, obesity, smoking and late-life stroke," said study author Dr. Alina Solomon of the University of Kuopio in Finland.

Another study presented at the neurology conference found that Alzheimer's starts earlier for people who have a history of heavy smoking and drinking. The study was based on 938 people 60 or older who were diagnosed with possible or probable Alzheimer's disease.

Those who had a history of heavy drinking developed Alzheimer's nearly five years earlier than people who were not heavy drinkers. Heavy smokers got Alzheimer's two years sooner.

People who smoked and drank -- and had a gene variant known to increase the risk of Alzheimer's -- developed the disease 8.5 years sooner than people who had none of these risk factors, the study found.

Source: Monifa Thomas, Health Reporter (mjthomas@suntimes.com) 21 April 2008 [FullText]

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