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April 17, 2008
Pfizer says study shows Lipitor has no significant impact on Alzheimer's
Pfizer (NYSE:PFE) Inc. said that the largest statin study of patients with Alzheimer's Disease shows that its blockbuster cholesterol-lowering prescription drug has no significant impact on the disease.
'In a study in patients with mild-to-moderate Alzheimer's disease (AD), the addition of Lipitor (atorvastatin calcium tablets) 80 mg to Aricept(R)(donepezil HCl) 10 mg showed no significant differences in cognition or global function (key measures of Alzheimer's progression) compared to placebo plus Aricept 10 mg.Lipitor,' the company said.
However, Pfizer, which is expected to report lacklustre sales of Lipitor in first-quarter results out later on Thursday, said the study further confirmed the safety profile of 80 mg doses of Lipitor in elderly patients.
The 18-month study included 640 patients and was the largest statin study in Alzheimer's disease.
Pfizer is attempting to build up its product pipeline as its patent for Lipitor expires in 2010.
Source: CNN Money & Thomson Financial delivered by Newstex. Newstex ID: AFX-0013-24562002 (17 April 2008) [FullText]
'In a study in patients with mild-to-moderate Alzheimer's disease (AD), the addition of Lipitor (atorvastatin calcium tablets) 80 mg to Aricept(R)(donepezil HCl) 10 mg showed no significant differences in cognition or global function (key measures of Alzheimer's progression) compared to placebo plus Aricept 10 mg.Lipitor,' the company said.
However, Pfizer, which is expected to report lacklustre sales of Lipitor in first-quarter results out later on Thursday, said the study further confirmed the safety profile of 80 mg doses of Lipitor in elderly patients.
The 18-month study included 640 patients and was the largest statin study in Alzheimer's disease.
Pfizer is attempting to build up its product pipeline as its patent for Lipitor expires in 2010.
Source: CNN Money & Thomson Financial delivered by Newstex. Newstex ID: AFX-0013-24562002 (17 April 2008) [FullText]
Labels: Cholesterol and AD
posted by Dr.Koudinov @ 17.4.08
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